We finally got to take his cone off and start to enjoy walks again fully and his paws turned back to their original colorwhite! We cannot imagine how horrible the situation for all would have been if we began this drug and our little buddy suffered any ill effects. Lets see the drug company Zoetis reported this: Zoetis Reports Fourth Quarter and Full Year 2014 Results There are a lot of factors to consider when trying to determine which is better for dogs Benadryl or Zyrtec. Itching and licking had gotten worse. The other option would have probably would have been a lot worse. Some medications may interact with . That is sad. My puppy is exhibiting the same bad side effects others mentioned in this post. It's an artificially synthesized substance that's injected into the body with the intention to cause changes in physiology and function. I am very much convinced Apoquel has caused the seizures. Seonaid, what dose are you giving your westie? Dog parent of 8 yrs, we just moved from VA to NC in the winter season. I went back to the vet and did an allergy test where we found out he is allergic to 19 things, including fish which was what he was eating. His previous blood tests (before Apoquel) were normal. 2 packs of apoquel tablets This again required an overnight stay at the vet center with a total cost of $2452.23 Good. You may even want to read about the legal definition of slander: http://definitions.uslegal.com/s/slander/. It did nothing for him and his nose continues to run in addition to him sounding like he is congested. Nowhere in the FDA stats on Apoquel does it claim that Apoquel is suppressing the immune system, and this caused pneumonia, mange, skin infection, bladder infection. She almost immediately stopped itching and I was delighted. Without that terrible Apoquel. The most common application of hydroxyzine for dogs is in relation to the treatment of pruritus. DO NOT GIVE THIS MEDICINE TO YOUR ANIMAL. Drugs that suppress the immune system Normal is 2.5 4.3. It can also be used for more long-term allergies but has varying results. Can Humans take Apoquel? 3.Regular bathing- of your dogs feet as he comes in from outside, and of your entire dog. Ive not noticed any of the side effects as of yet but after reading the comments, I will ask for blood work. My dog (66 lbs boxer/hound mix) is prescribed apoquel daily by her current vet for allergies. I love my dog way too much to simply take the risk. We had to use the Apoquel because he needed surgery for a torn ACL and couldnt use prednisone. I started looking at this site or blog for answers for the insane paw licking my baby goes through every year around Aug., Sept. One more thing I would like to say is that he was eating those CET dental sticks for about a year and a half before this whole skin issue started and I wonder if they caused anything to happen with his skin? I took her to the vet and they ran tests which all came back negative. This is where we get our information. Being very worried, I began doing research on the Apoquel the vet had given her and was shocked to find out its an immunosuppressant with some ugly side effects. All dogs itch sometimes, but when you notice it happening more and more, it could be a sign of a medical condition. I think I will try those probiotic and omegasits worth a shot. If the wind blows the wrong way she starts breaking out. I have taken him off of it for 3 weeks now due to low funds, and was going to put him back on them this weekend. Question: Can My Dog Take Apoquel And Zyrtec Quick Answer: Can Dogs Take Zyrtec Hydroxyzine And Apoquel Together Question: Can Give Dogs Zyrtec Question: How Much Zyrtec Give Dog Is It Safe To Gove A Dog Zyrtec And Apoquel Can U Give Dogs Zyrtec Can Zyrtec Give Dogs Diarrhea Miscellaneous Travel Tips During Covid 2022 Tips for Bike tour in the USA However, it is important to make sure that you are using the correct dosage for your dog's weight and that you are monitoring your dog closely for any side effects. Apoquel is safe to use in dogs one year and older. He is so sick he cant pick his head up. Two of my staffies have been put on these tablets but after reading all these comment Im stopping them. What brand of hepaticlear do you use and and do you give the chewable form? My vet has referred us to a vet specialist, which I hear is very expensive. I asked at one point how this worked and was told that it lowered the immune system to keep the itch mechanism from affecting the dog. But the principle is to think simple, minimal ingredients, avoid artificial colors, flavors and preservatives. She had gained 17lbs since July. I talked with a Homeopathic vet about my dog and this med and she said that she is seeing at least 4 dogs a week that are coming to her because of reactions to APOQUEL. I used some anti inflammation drops I had left over from dermatology vet and they seemed to be working but it is short lived and the yeast is still there. When I do find him upstairs he is comatose and has vomited all around the house and done a poo in the family room. Yes, Apoquel and Gabapentin can be used together for dogs - as there is no known interaction between the two drugs. The US Food and Drug Administration (FDA) has not placed any time restrictions on the use of Apoquel. So in the midst of all of this I did notice that her pet food had changed gradually and I finally took the last case back and put her on another food just in case it was a food additive issue! After 24 hours at one vet and no improvement, I Took him to a teaching hospital today and they laid it all out.he likely has aspergillosis, a fungal infection, that can either cause a nasal infection with drainage, sneezing, bleeding etc, or cause a systemic infection. She started having breathing problems and at the vet was so bad they had to give her oxygen. Topical Solutions Use a topical product that works to calm the source of the itchy skin and inflammation. How can these drug companies not predict psychiatric effects when they are messing with these systems???? Probably more concerned with the monthly sale of Apoquel to me rather than reporting this AE. After months of tests and other ways to treat the glands the vet finally linked the gland issue with the allergies so 2 weeks ago he put him on Apoquel. He had stopped eating and drinking. My Beagle Shorty was put on Apoquel for slight itching and minor hair loss around the middle of his ears. Not risking it !!! Im wondering if anyone has had luck with a very low dose achieving less itching with less side effects? document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Dogsnet is a participant in the Amazon EU Associates Programme, an affiliate advertising programme designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.co.uk Dogsnet is also a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com. My five-year-old German Shepherd developed skin allergies right after her first birthday. Worst of all she has gone instantly blind. Trazodone and acepromazine can be used together in some cases for dogs who are very anxious or aggressive, but this needs to be done in close consultation with your veterinarian in terms of dosing.If your dog requires strict crate rest, ask your veterinarian to prescribe trazodone. Well I got home and gave her, her first dose not much longer after that she seemed higher than a kite, a few hours later she started throwing up clear foaming liquid (about 6 times in total from afternoon through out the night) she hasnt eaten anything, she licks at her lips quite a bit until she settles and has body shakes. There is a wide variety of reasons your dog may be itchy. DrugBank Accession Number. You'll need to go back to whatever veterinary doctors are available and have them make sure they've not missed an underlying cause to the itch. Fingers crossed she wont have any lasting problems from this drug. We gave it a try because her itchiness was causing almost a seizure like problem. How long has this been a concern? Can you tell me a little more about the dog's situation? Drug interactions Hydroxyzine magnifies the effects of sedatives and inhibits the effect of stimulatory medications. dog? By June 20th(last dose), he was lethargic and would cry when we put our hands on him to love him. We live in Florida and this past winter he had no skin issues. This year is especially bad. Has anyone else has had similar issues? Long-acting benefits. I weaned her off the Hydroxyzine and started her on the Apoquel. I have found others not just on this web site that are questioning the same thing. Despite providing the vet center with a copy of my letter to Zoetis and their request to have the vet contact them to discuss this AE, as of 9-6-19 the vet has not contacted them. The vet prescribed Apoquel and after 2 weeks she never itches. Hydroxyzine for dogs is a canine antihistamine. The Apoquel seemed to stop her from itching but not completely and if we missed a dose which was very rare she would start itching again. He cant come down the stairs or jump on the bed. Two days later he was at deaths door. I knew the potential for problems but was willing to do anything make her comfortable, and hoped that she would not show any negative effects. The bigger question for us is though, why are all of these dogs suddenly being so effected by allergies? No drug is totally safe. Prednisone is a steroid and Apoquel is an immune modulator drug that specifically targets the receptors on your pets skin that cause itching. Apoquel is suppressing the immune system, and this caused pneumonia, mange, skin infection, bladder infection. Then Vet encouraged us to continue every 2nd day which we did. Feed your dog a simple food that he is less likely to react to. Apoquel side effects listed for dogs in the product insert include: vomiting, diarrhea, lethargy, anorexia, SQ or dermal masses (unspecified), decreased leukocytes, decreased globulins, and increased cholesterol and lipase. Went back to vet and they wanted her to go to specialist which she did this week.only wanted to run $2000.00 of allergies testbut vet didnt even put their hands on her.. Didnt think much of it until I watch her over the weekendOMG this baby was having a seizure !!!! Just look at the case of mefloquine in humans; a drug which blocks receptors in the CNS being given to control malaria!!! i have a newfie who was poisoned by our landlord with outdated illegal weedkiller- at 8mos we almost lost her since that episoed she had become a chronic alergic dog, and not to fleas -environmental stuff -mildew,mold,pine needles .etc. Chlorpheniramine is an antihistamine, used to treat allergic skin disease in dogs . She has NEVER done this, she wont even puke on the floor she runs to her crate she is the most courteous dog when it comes to messing anything up. I tried weening him off the Apoquel but after a few weeks he started getting worse. I just feel I needed to share these issues just in case anyone else has a pet that is suffering these same or similar symptoms. My Yorkie/jack Russell, around 8 years old is supposedly allergic to fleas, around 20lbs. Swelling and inflammation. Yes, it stopped his itching but at what price? His skin is scaley and flakes like crazy. Wow my eyes are wide. Tried everything else. I started looking at this site or blog for answers for the insane paw licking my baby goes through every year around Aug., Sept. There are very few side effects of cefpodoxime, however it may cause complete loss of appetite in cats which can lead to serious complications. So, it is important that you only give this medication to your dog under your vets supervision. Noticeably happier and energetic. It seems vets are putting dogs on it right and left, and while it may help with those symptoms..new ones develop that can be far worse. These drugs were first discovered in the 1930s. Finally after several hours he ate his food and drank enough water. Zyrtec, Claritin, and Benadryl are just some of the meds that both humans and dogs can take safely. But, your dog may be displaying signs of anxiety because of discomfort. What are the side effects of hydroxyzine in dogs? Because of these problems I wouldnt suggest anyone take the risk and use this drug. We adopted this puppy from the Animal Defense League 2/16/2016. In that years time though, she is constantly asking for food, drinks excessively, when she lays down to sleep her breathing sounds like she has an obstruction in her airway. I recently brought him to the vet because he hasnt been himself as the before mentioned concerns. To all dog owners WARNING do not give your dog Apoquel . I was assured this drug was safe. We think its the right thing to do. The safety and efficacy of Apoquel has not been evaluated in humans, and it is not recommended for use in people. I was never told this drug is an immunosuppressent. Blood work showed he was in severe liver failure with liver enzymes and glucose levels very high. My dog has the latter. I guess I need to do some more research. It was attached to the muscle and she didnt cut into it because of the location of the tumor. Not like her at all. I hope we stopped this drug in time before more serious damage happens. I took him to my vet who then sent me to Emergency. Yes, you can give your dog Apoquel and Zyrtec together. Our vet may make over250,000 a year. In less than 7 days this drug killed our baby. If worse I will probably take her off it. The study she pulled said 10% of dogs will develop these tumors with Apoquel. I looked thru the glass and her little head rose up and She gave me a smile and wagged her tail and laid her head down. He also has a nodule on his spleen which will now be getting investigated. I had to put down his older brother in June and he the constant scratching, pulling his hair out, making himself bleed by biting and scratching himself. You can check http://www.orthomolecular.org for more research and info. At the beginning, our vet told us to give him the pill twice daily for the first week, and then once a day after that. About 30 minutes later, I woke up to find her sitting up in the bed just staring off into space and whining. Thats terrible! She has bumps down her back and you cannot touch her or brush without her lowering herself like it hurts. She would trip out the doorbumble around in the yard and occasionally just trip and stumble while she was searching for a place to do her business. In late December this same dog went into panic attacks while we were gone that we witnessed via video cams in our house where he shook violently, breathing heavy and labored and he began to find ways to get out of the house. He was diagnosed with severe pancreatitis. I have also found that if we keep his paws shaved or very short that helps tremendously. For the most part hes back to being our happy, playful puppy. It was a blistery, painful looking infection. Ahh me She began to develop ear infections and a vulvar fold infection neither of which had she ever had. He has now lost hair all over his body. For the appropriate Apoquel dosage, your vet will determine that based on the weight of your dog. old Golden Retriever just started taking it and it has made him lethargic as noted in this article. She had a check up and we were told everything was good. I went to the FDA website and there is not one complaint that I can find from any vet or pet owner. It has been launched with much fanfarefrom Zoetis.. FDA Approves APOQUEL (oclacitinib tablet) to Control Itch and Inflammation in Allergic Dogs, Zoetis Offers a Targeted New Approach to Rapidly and Safely Stop the Cycle of Itch and Inflammation Associated with Allergic Skin Disease in Dogs. Its all about the money! A vet gave my dog hydroxyzine because he was licking his paw a lot. It was like a miracle drug. The pills are gone and I am unable to afford another $200+ vet visit plus a larger supply of Aproquel. Dogs have 10 times more mast cells on their skin than people do. X27 ; s situation also has a nodule on his spleen which will now be investigated. And efficacy of Apoquel tablets this again required an overnight stay at the vet prescribed Apoquel and zyrtec.. A lot effects of hydroxyzine in dogs times more mast cells on their skin than do! For blood work showed he was licking his paw a lot worse guess! 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